Thursday, July 5, 2018

j b s haldane


Prof. J.B.S. Haldane, 72, Dies; British Geneticist and Writer; Developed Simple Treatment for Tetanus—Marxist Quit His Homeland for India
DEC. 2, 1964


BHUBANESWAR India Dec. 1 —Prof. J. B. S. Haldane the worldfamous British geneticist died of cancer today at his home here. He was 72 years old.
Facially Professor Haldane resembled Rudyard Kipling; epigrammatically he took after George Bernard Shaw; politically he followed Karl Marx; but in science he was indubitably John Burdon Sanderson Haldane.
Biologist biochemist geneticist and sage of science in general Professor Haldane was a daring experimenter with himself as his own chief rabbit “It is difficult ” he once said by way of explanation “to he sure how a rabbit feels at any time. Indeed many rabbits make no serious attempt to cooperate with scientists.”
He was moreover ” an indefatigable writer about science for the layman.
He made lasting contributions in human physiology bydeveloping a simple treatment for tetanus (lockjaw) by laying the groundwork- for highpressure oxygen therapy and surgery and by pioneering the principles of the heartlung machine now widely used in heart and brain surgery.
In genetics he was the first to discover linkage in mammals to map the human chromosome and to measure the mutation rate of a human gene. He also contributed to studies in human physical endurance and defenses against mustard gas and lie demonstrated the importance in terms of survival of deep bomb shelters in wartime.
Equally notable were his indirect contributions as a stimulant and teacher for more than 40 years in Britain and in India. His students and his colleagues regarded his imind as luminous and lucid and his ideas as suggestive and succinct. Honored and decorated he became a philosopher of the life sciences shaping new pathways for biology and genetics and pointing to new directions for research in evolution.
In this respect Professor Haldane counted human inequality as a blessing. “I believe that any satisfactory political and economic: system must be based on the recognition of human inequality ” he said in one of his last public lectures. He explained that “as our understanding of genetics increases we shall I believe see that that society is freest in which opportunity for acting according to one's genotype hereditary makeup] is maximized.”
This appeal for the recognition of innate diversity could well have stemmed from Professor Haldane's own life. He was born and reared in a British society that refused to be confined by The Establishment. Individualism even eccentricity was its hallmark.
Of Scottish ancestry Professor Haldane was born at Oxford on Nov. 5 1892 the son of Dr. John Scott Haldane a physiologist and mining expert who developed the decompression method used to avoid “the bends” in divers.
His sister was Naomi Mitchison a novelist; his uncle was Viscount Haldane once Lord Chancellor under a Labor Government. Professor Haldane attended Eton and New College Oxford taking his degree in the classics.
He learned science by apprenticeship. He assisted his father from the age of 8 onward until he began formal research in 1910. His career was interrupted by World War I in which he fought as a member of the Black Watch. He was wounded and gassed twice and was mustered out as a captain in 1919.
It was after this experience during the war that he became an expert on mustard chlorine and other gases.
After the war he became a Fellow of New College and from 1922 to 1932 he was a Reader in Biochemistry at Cambridge.
There he was the center of a cause celebre. He was dismissed for “gross immorality” in 1925 after being named corespondent in an undefended divorce suit involving Charlotte Franken a writer. Supported by G. K. Chesterton Bertrand Russell W. L. George and other notables Professor Haldane won a reversal of his ouster and established the precedent that the private life of a Cambridge professor was to be considered as having nothing to do with his work at the institution. Miss Franken and the professor were .married shortly after his vindication.
After a year as visiting professor at the University of California in 1932 a year in which he was elected a Fellow of the Royal Society he returned to Britain as a professor first of physiology then of biometry at London University where he remained until 1957 when he left Britain for India in a huff over the presence of American troops on British soil.
Departing London for Calcutta near where he later set up a laboratory and home Professor Haldane said: “I want to live in a free country where there are no foreign troops based all over the place; yes I do mean Americans.”
He became an Indian citizen wore Indian garb fasted on occasion in the Gandhi manner and lived quietly with his second wife the former Helen Spurway a science colleague he married in 1945 after Miss; Franken divorced him There were no children by either marriage
As a scientist Professor Haldane believed in finding out things for himself. To study fatigue he once shut himself for . long periods in a tight chamber the air charged with carbon dioxide. Early in his career he poisoned himself by swallowing bicarbonate of soda and hydrochloric acid and found that ammonium chloride could cure convulsions in children. At one restless point in his life in 1927 he underwent a bloodtransfusion test in which blood was transferred from one part of his body to another.
In trying to find a cure for diabetes he allowed himself to be put into a diabetic condition and then operated on without anesthetic so other doctors could carry out tests on him.
In addition to winning wide acclaim for his popular science books he was also considered the chief modern writer on evolution.
Professor Haldane was a burly tweedy shaggy man with a remarkably large head. Describing himself in 1940 he wrote “I measure 6 feet 1 inch weigh 245 pounds; - and enjoy swimming arid mountain walking. I aim bald and blueeyed with a clipped mustache; a moderate drinker and a heavy smoker. I can read 11 languagesand make public speeches in three; but am unmusical. I am a fairly competent public speaker.”
He might have added that he also liked to tweak Ameri” cans. “The trouble with your school system ” he once remarked to an interviewer in New York “is based on its failure to recognize that children differ from one another. Every child receives the same training—an obvious error. In itself it is an indication of your genetical ignorance.”
Professor Haldane's serious shafts were usually directed to upholding the concept of a pluralistic genetic society in which science would be man's servant. “It is easier to alter the social organization than to alter human beings’ he said.
In a Shavian aphoristic manner he observed that “the genetic heaven must be a place in which there is room for all sorts of people each best at something or other.”
“There is not any perfect man except in relation to tasks and environment ” he insisted contending that “a feebleminded strong man would give a better account ofhimself in the Darwinian natural struggle for existence than a physically weak intellectual.
Arguing the virtues of diversity with a homely example he once remarked:
“You cannot havea successful .marriage unless the wife is better than the husband at some things. For example I cannot cook or play the piano like my wife but on the other hand she is not as good a mathematician as I am. Mutual respect is what you want all through society.”
From this he concluded that “the society that enjoys the greatest amount of liberty is the one that permits and respects the greatest amount of polymorphism ” or variety in human forms.
Outlining his genetic and social credo said:
“I do not believe in uniformity. I think the more individuals in the world the better. If there is one lesson man can learn from the animals it is just this: You have all sorts of dogs—shepherd dogs wolfhounds Newfoundland dogs dachshunde terriers and St.! Bernards.
“Would anyone think of producing only one species of dog and call it the perfect dog eliminating all the others? What makes human life amusing is getting all these varieties of dogs into one family. And the hope for humanity is that that sort of a thing should go on not only among dogs but among human beings as well.
“If we have any lesson -to learn from animal and plant genetics it is that there is not any one best type in the species. On the contrary we have various environments and various species to fit into them.”
Professor Haldane wanted man to control science for his own benefit. “While man does not yet know how to control his own evolution ” he once asserted “it behooves us to begin thinking about what we should do’ when the time does come as it probably will when this knowledge becomes available to us.
“If we had discussed in advance what we should do with nuclear energy long before we knew how to use it we might have agreed in advance not to use it in atomic bombs and would have gone a long way toward solving the problem we face today.”
Early in his career Professor Haldane developed scorn for Nazi racial tenets. “The doctrine of the equality of man although clearly untrue as generally’ stated has this much truth—that on a knowledge of their ancestry we cannot yet say one man will and another man will not be capable of reaching a given cultural standard.”
This conviction plus the climate of opinion in liberal circles in Britain in the 1930's plus his own reading in Marx Lenin and especially Engels drew the scientist toward sympathy with the British Communist party.
In the middle thirties he announced that he was a Marxist a description he applied to himself in 1964. He joined the British party in 1942 served oh the editorial board of The London Daily Worker until 1949 and wrote numerous articles for that payer and The Daily Worker in. New York mostly on scientific subjects. He cooled toward official Communism as time went on and declined to accept the biological notion of Prof. Trofim D. Lysenko the Soviet biologist that characteristics produced by environment can become hereditary. He left the party toward the end of. the 1940's.
‘Cured’ by Lenin
As a Communist writer Professor Haldane could make outrageous remarks with an apparent straight face as when he wrote that Lenin had cured him of gastritis.
“I had it for about 15 years ” he said “until I read Lenin and other writers who showed me what was wrong with our society and how to cure it. Since then I have needed no magnesia.”
Although he insisted that Marxism contained a working hypothesis for scientific research and application—a view he expounded at some length in “The Marxist Philosophy and the Sciences” in 1938—he was by no means a dogmatist nor did he quote patristic utterances.
Professor Haldane had a certain amount of wry humor about himself “I cannot deny the possibility but at no time in my life has my personal survival seemed to me a probable contingency ” he once said. And toward the close of his life after he had been operated on for a particularly painful cancer he wrote a doggerel in which he said “My final word before I’m done /Is ‘Cancer can be rather fun.’’“ Then he added “I know that cancer -often kiils /But so do cars and sleeping pills.” He titled his verse ‘‘Cancer's a Funny Thing!” v
Professor Haldane held many academic honors; In addition to being a Fellow of the Royal Society he was a corresponding member of the Societe” de Biologie -the Deutsche Akademie der Wissenschaften the National Institutes of Sciences of India the Royal Danish Academy of Sciences; and an honorary member of the Moscow Academy of Sciences.
He held honorary degrees from Oxford the Universities of Paris Edinburgh and Groningen. He wore the Darwin Medal of the Royal Society the DarwinWallace Commemorative Medal of- the Linnean Society and the Kimber Medal of the United States National Academy of Sciences. He was also made - a chevalier of the Legion of Honor in 1937. for his scientific services to France.
At his death he was head of the Genetics and Biometry Laboratory of the Government of Orissa India.
In addition to numerous papers in scientific journals Professor Haldane's principal books were: “Daedalus” (1924); “Callinicus” (1925); “Possible Worlds” (1927); “Animal Biology” (with J. S. Huxley 1927); “Science and Ethics” (1928); “Enzymes” (1930); “The Inequality of Man” (1932); “The Causes of Evolution” (1933); “Fact and Faith” (1934); “Heredity and Politics (1938); “Science and Everyday Life” (1939); “New Paths on Genetics” (1941); “Science Advances” (1947) and “The Biochemistry of Genetics (1953).

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